Appendices of the nipple and areola of the breast in Neurofibromatosis type 1 patients are neurofibromas.
نویسندگان
چکیده
In NF1-patients, tumours arising in the areola region of the breast often appear similar to the nipple. The aim of this study was to analyse tumours of this region. Eighty-three specimens from 55 patients with NF1 were analysed [females: 42, males: 13, mean age of the total group: 41.6 years, range: 4-62 years]. NF1 patients with apparent extensive affections of the breast who received debulking procedures for disfiguring invasive or superficial plexiform neurofibroma were excluded. All specimens were found to be composed entirely from neurofibromas with no residues resembling segments of glandular structures. Following ablative surgery, no local recurrence was noted within a follow-up period of 10 years. Tumours arising in the areola and nipple area and mimicking an accessory nipple were all neurofibromas. Local excision of neurofibromas was adequate to relief patients from an often unsightly appearance.
منابع مشابه
Neurofibromatosis of the nipple-areolar area: a case series
INTRODUCTION Neurofibromatosis type 1 is an autosomal dominant disorder that occurs across all ethnic groups and affects approximately one in 4000 individuals. One of the most noticeable characteristics of the disease is the development of neurofibromas. CASE PRESENTATION A total of 258 patients (131 women, 127 men) with neurofibromatosis type 1 were evaluated between 1994 and 2004 in our hos...
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متن کاملهیپرکراتوز دو طرفه نیپل و آرئول پستان: گزارش مورد
A 25-year-old woman with a history of five years of bilateral verrucous hyperkeratosis and darkening of both nipples and areolae is reported herein. The histopathology was suggestive of hyperkeratosis of areola and nipple. Hyperkeratosis of areola and nipple is a rare condition which is seen unilaterally or bilaterally in both sexes. Three types of hyperkeratosis of areola and nipple are descri...
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ورودعنوان ژورنال:
- Anticancer research
دوره 30 5 شماره
صفحات -
تاریخ انتشار 2010